Catalyst is an amazing tool in its ability to control serial. Since however serial connections and cables are not standardized, you can run into real trouble trying to figure out an error on site.
Unless you have reliable control software to test your serial connections, it is best just to leave serial to those who use it day in and day out. If you do decide to use serial, buy your cables and adaptors pre-made instead of making them yourself. Also make sure you have a hand full on null modems for each size you use. Also remember that a cable that changes from one size DB to another doesn't guarantee the pin configuration will be correct.
For a while I actually carried a little box with me that allowed me to switch serial pin-outs and DB sizes. I'll throw up a picture when I find it. Some serial software will actually allow you to change the pin-outs automatically. Catalyst as amazing as it is, doesn't really have a need for this so you'll have to find other tools to test with.
(Please note edits in italics)
TODD SCRUTCHFIELD 
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Originally Posted by SourceChild
