Once you reboot any Mac no matter what Mac it is, and you do not have an output device (or proxy such as a detective or parrot), Catalyst will not work.
There are situations with VGA monitors where you can disconnect while the system is on and reconnect without issue. Otherwise, you must have something connected for the GPU to report to Catalyst that the system is working.
Note you will also see this same kind of crash if your show file has a dual output config but you boot with only one monitor attached.
UPDATE: This was only happening in m331. Not an issue using a different build.