I'm running into an issue where the longer the Black Magic input is turned on, the more latency it acquires. If I turn off the input, then turn it back on, it resets. I have not yet gone through BM drivers to try other versions. I'm assuming it's some so memory leak within the BM drivers. My current setup is:

Trash Can Mac Pro 2013, D500 GPUs.
Catalyst n546
OS 10.9.5
BM UltraStudio 4k
BM Driver 10.4.1

Thanks everyone -