Nothing has changed in that respect - it is still possible to use 2 networks.
Catalyst used to show the IP address of the network adaptor at the top of the service order - now it doesn't due to the OS - but that doesn't affect any functionality
Just ignore what is says at the top of the Catalyst Control window (unless you are using en0)

Artnet:
Artnet is a broadcast protocol - so the sending device will 'broadcast' to all receivers with a network adaptor with a valid IP address in the correct range.
If unicast - its point to point and the destination is specified by the source anyway.

When transmitting from PixelMad, you should ensure that you select the correct broadcast IP range (i.e. 2.255.255.255 - not 255.255.255.255 if using multiple networks.)

Sync Data:
There is a 'remote' drop-down menu in the catalyst control window allowing you to choose the IP address range and subnet through which to transmit.
Again - so long as you setup a network adaptor with the correct IP address and subnet, the network traffic will be transmitted though the correct adaptor (network interface)


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