It would appear,through limited testing, that the lfg cards work fine in snow leopard. Haven't done anything crazy but all 8 of my inputs seem to play nice.. I did notice that some of the input fx had issues like leaving trails etc but this resolved itself after a reboot... not sure what to think. On a side note, turning on input fx did crash my leopard os on same machine... seems like I remember reading something about that.. whats the deal?